Public transportation systems create an environment in which large numbers of persons on a daily basis share space and interact with surfaces found within system vehicles. A recent study in the United Kingdom demonstrated an increase of respiratory infections (colds and flu’s) to persons if they had ridden in a bus or streetcar five days previously (Troko et al., 2011). The immediate reaction is to step up cleaning protocols and application of disinfectants. AEGIS provides protection between cleaning. It is a new layer of defense when fighting this challenge.